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Behavioral Neurobiology of Bipolar Disorder and its by Husseini K. Manji, Carlos A. Zarate Jr.

By Husseini K. Manji, Carlos A. Zarate Jr.

This booklet bargains the main updated information regarding examine surrounding the neurobiology of bipolar illness in addition to presently on hand and novel healing thoughts. the amount has assembled a generally revered workforce of preclinical and scientific researchers who carry their services to undergo upon this ailment by means of reviewing state-of-the-art learn and scientific proof concerning the pathophysiology and remedy of bipolar illness. Early chapters evaluation the path and final result and genetics of this hugely heritable situation, together with chapters on epigenetics and scientific endophenotypes. numerous chapters supply a remarkably thorough and certain review of the neurobiology of the ailment, together with what's identified from neuroimaging paintings and the advance of animal types. ultimately, the publication covers remedy options for bipolar sickness, together with either conventional and novel therapeutics, in addition to non-pharmacological remedies. It bargains either researchers and clinicians key insights into this devastating ailment.

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Behavioral Neurobiology of Bipolar Disorder and its Treatment (Current Topics in Behavioral Neurosciences, Volume 5)

This ebook bargains the main updated information regarding study surrounding the neurobiology of bipolar illness in addition to at the moment to be had and novel healing concepts. the quantity has assembled a broadly revered team of preclinical and scientific researchers who carry their services to endure upon this disorder by way of reviewing state of the art study and scientific facts in regards to the pathophysiology and therapy of bipolar illness.

Additional info for Behavioral Neurobiology of Bipolar Disorder and its Treatment (Current Topics in Behavioral Neurosciences, Volume 5)

Sample text

1 Redefining the Phenotype . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Novel Molecular Tools . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Novel Analytical Tools . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 5 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 References .

27 5 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Abstract In this chapter, we will attempt to outline the current state of genetic knowledge for bipolar disorder and briefly summarize the main findings from genetic epidemiology studies. We then review the most recent original literature, based largely on genome-wide association study methods.

27 Abstract In this chapter, we will attempt to outline the current state of genetic knowledge for bipolar disorder and briefly summarize the main findings from genetic epidemiology studies. We then review the most recent original literature, based largely on genome-wide association study methods. We conclude with some ideas about future directions. 1 Introduction There is a broad consensus that the etiology of bipolar disorder (BPD) has a genetic basis.

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